


Comparison of SERVE-HF and ADVENT-HF Trials Aspect SERVE-HF Trial ADVENT-HF Trial Population Studied Heart failure patients with reduced ejection fraction (HFrEF) and predominant central sleep apnea (CSA). Heart failure patients with sleep apnea (central and obstructive sleep apnea [OSA]). Primary Objective Evaluate the impact of […]

Comparison of Findings: SAVE, RICCADSA, and ISAACC Trials Aspect SAVE Trial RICCADSA Trial ISAACC Trial Population Studied OSA patients with established cardiovascular disease (CVD). Coronary artery disease (CAD) patients with nonsleepy OSA. Acute coronary syndrome (ACS) patients with OSA. Primary Objective Assess whether CPAP reduces […]